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Title | COTELLIC® (cobimetinib) for BRAF V600E or V600K(+)(+) Metastatic Melanoma |
Description | Find tools and information for COTELLIC® (cobimetinib) + Vemurafenib, a combination treatment for BRAF V600E or V600K(+) unresectable or metastatic melanoma. Important: If your healthcare provider prescribes ZELBORAF (vemurafenib), also read the Medication Guide that comes with ZELBORAF. What is COTELLIC? COTELLIC is a prescription medicine that is used with the medicine ZELBORAF, to treat a type of skin cancer called melanoma that has spread to other parts of the body or cannot be removed by surgery, and that has a certain type of abnormal “BRAF” gene. Your healthcare provider will perform a test to make sure that COTELLIC is right for you. It is not known if COTELLIC is safe and effective in children under 18 years of age. Important Safety Information: Avoid sunlight during treatment with COTELLIC and ZELBORAF. COTELLIC and ZELBORAF can make your skin sensitive to sunlight. You may burn more easily and get severe sunburns. When you go outside, wear clothes that protect your skin, including your head, face, hands, arms, and legs. Use lip balm and a broad-spectrum sunscreen with SPF 30 or higher. COTELLIC and ZELBORAF may cause serious side effects, including risk of new skin cancers, risk of other cancers, bleeding problems, heart problems, allergic reactions, severe rash and other severe skin reactions, eye problems, changes in the electrical activity of your heart (QT prolongation), liver problems or liver injury, muscle problems (rhabdomyolysis), skin sensitivity to sunlight (photosensitivity), worsening side effects from radiation treatment, kidney injury, and connective tissue disorders. Tell your doctor if you are pregnant or plan to become pregnant, as COTELLIC and ZELBORAF can harm your unborn baby. Females who are able to become pregnant should use effective birth control during treatment with COTELLIC and ZELBORAF and for 2 weeks after the final dose of COTELLIC or ZELBORAF (whichever is taken later). Do not breastfeed during treatment and for 2 weeks after the final dose of COTELLIC or ZELBORAF (whichever is taken later). Talk to your healthcare provider about the best way to feed your baby during this time. Tell your healthcare provider about all the medicines you take. Some types of medicines will affect the blood levels of COTELLIC. Common side effects of COTELLIC in combination with ZELBORAF include diarrhea, sunburn or sun sensitivity, nausea, fever, and vomiting. COTELLIC and ZELBORAF can also cause changes in blood test results. Tell your healthcare provider if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of COTELLIC and ZELBORAF. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or www.fda.gov/medwatch. You may also report side effects to Genentech at (888) 835-2555. Please see both Full COTELLIC Prescribing Information and Patient Information and Full ZELBORAF Prescribing Information and Medication Guide for additional Important Safety Information. |
Keywords | Cotellic, Zelboraf, cotellic zelboraf, vemurafenib, cobimetinib, BRAF V600E, V600K(+), metastatic melanoma treatment, Genentech, cobi, BRAF, resources, Genentech Access Solutions, unresectable melanoma treatment, cancer, oncology, cancer treatment |
WebSite | www.cotellic.com |
Host IP | 72.34.128.116 |
Location | San Mateo, California, United States |
Site | Rank |
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US$8,098
Last updated: Jun 30, 2020
Cotellic.com has global traffic rank of 4,186,753. Cotellic.com has an estimated worth of US$ 8,098, based on its estimated Ads revenue. Cotellic.com receives approximately 739 unique visitors each day. Its web server is located in San Mateo, California, United States, with IP address 72.34.128.116. According to SiteAdvisor, cotellic.com is safe to visit. |
Purchase/Sale Value | US$8,098 |
Daily Ads Revenue | US$4 |
Monthly Ads Revenue | US$133 |
Yearly Ads Revenue | US$1,619 |
Daily Unique Visitors | 739 |
Note: All traffic and earnings values are estimates. |
Global Rank | 4,186,753 |
Delta (90 Days) | 0 |
Most Popular In Country | N/A |
Country Rank | N/A |
Host | Type | TTL | Data |
cotellic.com | A | 3599 | IP: 72.34.128.116 |
cotellic.com | NS | 3599 | Target: ns1.roche.com. |
cotellic.com | NS | 3599 | Target: hlrns1.roche.com. |
cotellic.com | NS | 3599 | Target: ns2.roche.com. |
cotellic.com | SOA | 3599 | MNAME: ns1.roche.com. RNAME: global.hostmaster.roche.com. Serial: 2020060601 Refresh: 10800 Retry: 3600 Expire: 604800 Minimum TTL: 3600 |
HTTP/1.0 301 Moved Permanently Location: http://www.cotellic.com/ Server: BigIP Connection: Keep-Alive Content-Length: 0 HTTP/1.1 301 Moved Permanently Content-Type: text/html; charset=iso-8859-1 Date: Tue, 30 Jun 2020 23:30:43 GMT Location: https://www.cotellic.com/ Server: Apache Content-Length: 233 Connection: Close HTTP/1.1 200 OK Accept-Ranges: bytes Content-Type: text/html; charset=UTF-8 Date: Tue, 30 Jun 2020 23:30:43 GMT Server: Apache Vary: Accept-Encoding Content-Length: 75089 Connection: Close |
Domain Name: COTELLIC.COM Registry Domain ID: 1862260306_DOMAIN_COM-VRSN Registrar WHOIS Server: whois.safenames.net Registrar URL: http://www.safenames.net Updated Date: 2020-06-11T00:08:36Z Creation Date: 2014-06-10T13:28:20Z Registry Expiry Date: 2021-06-10T13:28:20Z Registrar: SafeNames Ltd. Registrar IANA ID: 447 Registrar Abuse Contact Email: abuse@safenames.net Registrar Abuse Contact Phone: +44.1908200022 Domain Status: clientDeleteProhibited https://icann.org/epp#clientDeleteProhibited Domain Status: clientTransferProhibited https://icann.org/epp#clientTransferProhibited Domain Status: clientUpdateProhibited https://icann.org/epp#clientUpdateProhibited Name Server: HLRNS1.ROCHE.COM Name Server: NS1.ROCHE.COM Name Server: NS2.ROCHE.COM DNSSEC: unsigned URL of the ICANN Whois Inaccuracy Complaint Form: https://www.icann.org/wicf/ Domain Name: COTELLIC.COM Registry Domain ID: 1862260306_DOMAIN_COM-VRSN Registrar WHOIS Server: whois.safenames.net Registrar URL: http://www.safenames.net Updated Date: 2020-06-11T01:08:36Z Creation Date: 2014-06-10T13:28:20Z Registrar Registration Expiration Date: 2021-06-10T13:28:20Z Registrar: Safenames Ltd Registrar IANA ID: 447 Registrar Abuse Contact Email: abuse@safenames.net Registrar Abuse Contact Phone: +44.1908200022 Domain Status: clientDeleteProhibited https://icann.org/epp#clientDeleteProhibited Domain Status: clientTransferProhibited https://icann.org/epp#clientTransferProhibited Domain Status: clientUpdateProhibited https://icann.org/epp#clientUpdateProhibited Registry Registrant ID: Not Available From Registry Registrant Name: Data protected, not disclosed Registrant Organisation: Genentech, Inc Registrant Street: 1 DNA Way Registrant Street: Registrant City: South San Francisco Registrant State/Province: CA Registrant Postal Code: 94080 Registrant Country: US Registrant Phone: Data protected, not disclosed Registrant Fax: Data protected, not disclosed Registrant Email: Global.domainmaster@roche.com Registry Admin ID: Not Available From Registry Admin Name: International Domain Administrator Admin Organisation: Safenames Ltd Admin Street: Safenames House, Sunrise Parkway Admin Street: Linford Wood Admin City: Milton Keynes Admin State/Province: Bucks Admin Postal Code: MK14 6LS Admin Country: UK Admin Phone: +44.1908200022 Admin Fax: +44.1908325192 Admin Email: hostmaster@safenames.net Registry Tech ID: Not Available From Registry Tech Name: International Domain Tech Tech Organisation: Safenames Ltd Tech Street: Safenames House, Sunrise Parkway Tech Street: Linford Wood Tech City: Milton Keynes Tech State/Province: Bucks Tech Postal Code: MK14 6LS Tech Country: UK Tech Phone: +44.1908200022 Tech Fax: +44.1908325192 Tech Email: hostmaster@safenames.net Name Server: hlrns1.roche.com Name Server: ns1.roche.com Name Server: ns2.roche.com DNSSEC: unsigned URL of the ICANN WHOIS Data Problem Reporting System: http://wdprs.internic.net/ Safenames - Experts in Global Domain Management and Online Brand Protection Domain Registration in over 760 different extensions Enterprise Domain Management since 1999 Mark Protect™ Online Brand Monitoring and Enforcement Domain Consulting and Strategy Domain Name Acquisition Domain Disputes and Recovery Visit Safenames at www.safenames.net +1 703 574 5313 in the US/Canada +44 1908 200022 in Europe By submitting this query, you agree to abide by this policy. |